An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15961 entries, 13944 authors and 1935 subjects. Updated: March 22, 2024

SUMNER, James Batcheller

1 entries
  • 14025

The isolation and crystallization of the enzyme urease.

J. Biol. Chem., 69, 435-441, 1926.

Sumner (Nobel Prize 1946) first isolated and crystallized an enzyme (urease) and proved that enzymes are proteins.

Sumner reinforced his discovery by recrystalizing urease, publishing a follow-up paper one month later:
"Note. The recrystallization of urease," J. Biol. Chem., 70, 1926, 97-98.

(Thanks to Juan Weiss for the follow-up reference.)




Subjects: BIOLOGY › MOLECULAR BIOLOGY › Protein Structure, BIOLOGY › MOLECULAR BIOLOGY › X-Ray Crystallography