A correction of the botanical errors of Pliny. Remembering the times in which Leoniceno lived, Garrison considers this work “a feat of the rarest intellectual courage”. It was accepted by later botanists and thus made possible scientific description of the materia medica. The second edition, edited by Ludovico Bonaccioli, [Ferrara: per Joannem Maciochium, 1509,] contains the first printings of Leoniceno’s responses to his critics in 1493, 1503, and 1507. These responses apparently circulated in manuscript until 1509. ISTC No. il00168000. Digital facsimile from the Bayerisches Staatsbibliothek at this link. Digital facsimile of the 1509 edition from Google Books at this link.